The xanthine derivatives are agents that resemble natural occurring xanthine such as caffeine, theobromine and methylxanthines. These are plant alkaloids and components of coffee, tea and chocolate.
They found wide application for treating bronchospasm caused by asthma or chronic obstructive lung disease. The widely used xanthine derivates are Caffeine and Theophylline.
Caffeine, also known as 1,3,7-trimethylxanthine, is a naturally occurring xanthine alkaloid that acts as a stimulant of the central nervous system. It is frequently consumed as a beverage or supplement for its stimulant effects and is marketed to improve energy, focus, and athletic performance; however, excessive consumption of caffeine can be extremely toxic.
It acts by inhibiting phosphodiesterase, antagonizing adenosine receptors, and releasing catecholamines.
| Product name | CAS No | Specifications |
|---|---|---|
|
Caffeine Anhydrous |
58-08-2 |
Inhouse, IP, BP, USP, EP |
It is 1,3-dimethyl-3,7-dihydro-1H-purine-2,6-diketone, and can be described as again dioxydimethylpurine, 1,3-dimethyl xanthine, 1,3-dimethyl xanthine etc.
It belongs to the methyl purine class of medications, has diuresis, cardiac stimulant, coronary artery dilator, stimulated main centre effects through systems, and can be used to treat bronchitis, pulmonary emphysema, bronchial asthma, and cardiac dyspnea.
| Product name | CAS No | Specifications |
|---|---|---|
|
Theophylline |
58-55-9 |
Inhouse, IP, BP, USP, EP |
Theobromine, also known by the name 3,7-dihydro-3,7-dimethyl-lH-purine-2,6-dione, is a xanthine compound, which also comprises caffeine and theophylline. Although the compound’s name is “theobromine,” it contains no bromine because the word is derived from Theobroma, the name of the cacao tree’s genus.
Theobromine can be used as a starting material to make pentoxifylline, a methylxanthine derivative. Pentoxifylline is used to treat intermittent claudication and vascular dementia by improving blood flow.
| Product name | CAS No | Specifications |
|---|---|---|
|
Theobromine |
83-67-0 |
IP, BP, USP |
6-Amino-1,3-dimethyluracil is a chemical used in the production of novel pyrimidine and caffeine derivatives with excellent anticancer activity. It is also employed as an intermediate in the production of fused pyrido-pyrimidines.
| Product name | CAS No | Specifications |
|---|---|---|
|
6-amino-1,3-Dimethyl Uracil (DMAU) |
6642-31-5 |
Inhouse |
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